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专访希氏异构:华西医院背后的人工智能团队

2018-05-24

 

xishiyigoudediyiciliangxiangjiuyinqilefeichangdadeguanzhu。

 

7yue26ri,cctv-1、xinhuashe、zhongxinshe、renminwang、kejiribaodengduojiameitibaodaolehuaxiyiyuanzaiyixuerengongzhinengjishushangdezhongdayanfajinzhanheyanfatixidegoujian。

 

huaxiyiyuanyuxishiyigougongsizaixiaohuaneijingyingxianglingyuderengongzhinengjishuyanfaqudetupoxingjinzhan,duiyuxiaohuaneijingxiadeduozhongjibingpandingzhunquedudadao95%zuoyou。huaxiyiyuanyuxishiyigougongsilianhechenglihuaxi-xishiyixuerengongzhinengyanfazhongxin,zaixiaohuaneijing、bingli、ct、mrichaoshengdengduolingyukaizhanlianheyanjiu,bujuweilaizhihuiyiliao。

 

jiyuhuaxi-xishidexiaohuaaijishudeguojishangdiyitairengongzhinengneijingyouwangnianneizaizhongguodansheng。

 

zuoweizhongguozuidingjideyiliaojigouzhiyi,huaxiyiyuancicidexinxipilu,wuyishiyigejinjunaiyiliaodezhongdaxinhao。neime,huaxidehezuofangxishiyigoujiujingshiyijiazenyangdeqiye?nenghuodehuaxideqinglai,xishiyigouyidingyouqiteshudedifang。

 

从多重角度看医疗AI

 

目前中国的医疗AI创业公司有很多,医疗AI这个领域有两个关键要素,就是“医疗”和“AI”。ruoshizhinengyongkaifangshidepingtaiquzuoyidianshujuxunlian,neibujiaozhenzhengzhangwoaijishu,ruoshibunenghuodeyiliuyiliaojigoudeshenduhezuo,neibujiaoyouhefadegaozhiliangdeyiliaoziyuan,zhiyouzheiliangzhexiangjia,caiyoukenengzuohaozheijianshi。

 

另外还有一个更为重要的因素,创业者一定要真正了解医疗行业的本质,yaoyoucongshangyedaojishuyingyong,yiduogeshijiaokanqingchuyiliaoxingye,fouzezuobuchengzheijianshi。

 

songjiezuoweiyiliaolinchuangyishengchushen,youyou20yunianyiyaoxiangguanxingyegaocengguanlijingyandechuangyezhe,zaicaifangzhongtayizhizaiqiangdiaoyiliaoaidexingyeyaosu。

 

 创始人 宋捷

 

xishiyigouchuangshirensongjiezaonianyuyixueyuanxiaobiyehouzuoweizhiyeyishicongshilinchuanggongzuo,houzoushangqiyeguanlidedaolu,90niandaizaizhongguoshekeyuangongdushangyejingjifangxiangyanjiusheng,10duonianqianzaizhongoushangxueyuan(ceibs)huodeembaxuewei,guoqudanrenguoduojiazhimingqiye、shangshigongsidegaoguan。

 

“20duonianqian,wozhuchiguoguoneizuizaodehisxitongdekaifa;15nianqianwozaiyijiazhimingdeyaoqizuofuzong;10nianqianwocongyanfakaishijinruyiliaoqixielingyu,woguanlidegongsihuodelegaixifenlingyudiyigeguojiaiiileiyiliaoqixiezhengshu;5nianqian,wocanyuleduojia3jiyiyuandechenggongbinggouxiangmu。

 

过去的经历,让我不会孤立地看待一个医疗技术的前景和发展路线。”宋捷或许是从技术研发、企业发展、医疗需求、经济回报多重视角看待医疗AI。

 

2015nian,gongsigangchenglideshihou,songjiebayanjiufangxiangdingweizailexiaohuadaoneijing。tazhisuoyizheimezuo,yifangmianshizhongguoxiaohuaxitongzhongliuzhanzhenggeexingzhongliufabinglvde43.5%,fabinglvgao、yiliaoxuqiuhenda。

 

lingyifangmianyuanyinshishoudaoleqixuexiong——yiweixiaohuajiequanweideyiliaozhuanjiadeyingxiang,gaizhuanjiayizhizaihuyu:zhongguoyinggairangjicengyiyuanjubeixiaohuaneijingdejianchanengli,yinweiduiyuxiaohuadaozaoqizhongliu,neijingjianchashizaozhenzaozhideweiyishouduan,zheileijibingruonengzaoqiganyu,yuhoufeichanghao,danruoshifazhandaoyouzhengzhuangerqujiuzhen,wangwangyijingshiquzuijiazhiliaoshijian。rangjicengyiyuanjubeineijingzhenduannengli,shixiaohualingyujishufazhandezhongzhongzhizhong。

 

danshiyishengdejingyandejilei,juefeiyicuerjiu,zuidadechengbenjiushishijian,yongaijishulaimibuyishengziyuandebuzu,zheishixishiyigouxuanzecongxiaohuaneijinglingyujinruyiliaodechushiyuanyin。

 

xingyundeshigongsichenglimeiduojiuguojidingjirengongzhinengkexuejiawurenboshituandui(yigoukejinovumind)quedingyiguquanhezuodefangshijiameng,congershidexishihuodeleguojiyiliuderengongzhinengxunlianjishu,gongsikaishijinrukuaisufazhanjieduan。

 

让AI找到疾病更多未知的关联

 

在产品研发的过程中,宋捷有自己的独特理解:“我从来不认为把医疗数据找一个开放的平台做一下训练就能获得真正有价值的模型(技术)。医学AI发展方向一定不是仅仅依靠人类对疾病的关联、特征的认识去让计算机对疾病做出判断,要知道人类对于自然的认识或许只有自然界本质的百分之几,倘若我们用这百分之几的‘经验’去‘规范’AI对自然的认识标准,那么AI的未来一定不会有突破。我们更希望AI能帮我们找到我们尚未认识到的疾病的更多的关联和最佳的治疗途径。

 

宋捷的这段话听起来似乎有些费解,为此他又解释道:“大多数同行做数据研究时都会请医疗专家标记疾病的具体特征,我们不会这样做,womenhuibajinkenengduodexinxirangjisuanjiquxuexi,jishiyouxiexinxirenleiyixuezhuanjiamuqianburenweiyuzheizhongjibingyoushenmeguanlian,danwomenxiangxin,yongzheiyangdeyanfasilu,aicainengfaxiangengduowomensuobuzhidaode‘dongxi’。aibenzhishigaoxiaolvdesiwei,erbushiduirenleidejiandanmofang。”

 

计算力带来的是倍数级的差异

 

xishiyigoudedongshi、zhuanjiaweiyuanhuizhuxiwurenboshishishijiejidejishudaniu,tashizuizaoliyonggpujinxinghailiangjiexidezhuanjiazhiyi,shiguojizhumingjisuanjiboyizhuanjia。cengdanrenmeiguohuipushiyanshizishenkexuejiajicudayanjiuzhongxinshouxiyanjiuyuan;cihouyingyaojiaruamdgongsi,lingdaoamdyigouxitongdeyanfatuandui,danrenamdyigouxitongshouxiruanjianjiagoushi。

 

 吴韧博士

 

2013nian9yue,wurenboshilikaiamdgongsi,shoubaidugongsiliyanhongxianshengyaoqing,zuoweibaidu“jiechukexuejia”jiarubaidushenduxuexiyanjiuyuan(institute of deep learning,idl)。

 

wurenboshituanduidejiarubujinweixishiyigoudailaile40duoweihaineiwaiyouxiudeaizhuanjiadeqiangdajishuzhichi,tongshiweigongsidailaichaoqiangdejisuannengli。

 

zhongsuozhouzhi,yixuetuxiangdeshujushihendade,biruyigeshuzibinglitupian,qidaxiaozaijigegbdaojishigegb,mianduihailiangdedashuju,duiyunsuannenglideyaoqiushihengaode。

 

songjiegaosudongmaiwang,suiranxianzaiyouhenduotigongyunjisuanfuwudejigou,birushuoali、yamaxundeng;yeyouzhuanmenyanfachaojijisuanjidechangshang,biruyingweida;tamendepingtai、chanpinjisuannenglihenqiang,danshitamenshitigongguangyudefuwuerbushizhuanmenyonglaichulitedingshujude。shiyonggongxiangdejisuanziyuan,wanchengtebiedadejisuanlianghenduoshihoushiyoukunnande。

 

希氏异构目前使用的超级计算机是吴韧博士设计的,宋捷表示,相比于使用云端的开放式计算平台和市场上产品化的高性能计算机的同行,希氏异构所使用的计算能力都数倍、十数倍于他人。

 

wurenboshibiaoshi:“congbenzhishangshuo,muqiandegezhongsuanfadoumeiyoutaidadequbie,nenggoudailaideaijishudechayiyejiushibaifenjidechayi;danshi‘suanli’dailaidechajuzeshibeishujidechayi。tongyangdeshijian,ruguonizhinengwanchengyiciaishujuxunlian,erwoyijingwanchenglehenduocidediedai,jishudeyoulieyimuleran!”

华西能够提供的不仅仅是数据

 

zhengshiyouyuxishiyigoutuanduidejishuyujingyanyoushi,huaxiyiyuanjuedingyuxishiyigouzhankaihezuo。2017nian,shousichuanshengzhengfuzhongdianfazhanshengwuyiliaochanyedezhengcexiyin,xishiyiliaozhuanyidaosichuan,2017nian3yue,sichuanxishiyigouyiliaokejiyouxiangongsizaichengdouyixuecheng(wenjiang)chengli。

 

与华西医院的合作,使得希氏异构获得了高质量医疗数据和一流的临床专家资源的支持,也正是以华西数据为基础,希氏异构才可以在不做局部标注的情况下,进行模型训练,最后获得效果得到华西医院的专家认可。

 

宋捷认为:“医疗专家在医疗AI研发方面的作用,绝不是提供一下数据,更不是做个图片的局部‘标注’,真正的价值是他们医疗研究的思路甚至是直觉,还有他们能告诉我们临床的真正痛点,这是技术应用的方向。在医学AI领域,医生的重要性甚至超过AI技术专家。

 

sichuandaxuehuaxiyiyuanxiaohuaneiketangchengweijiaoshoujieshaoshuo:“tongguohuaxi—xishineikuiyingxiangjishipinzhinengxitong,duijingtaitupianhedongtaishipinzuochutishihepanding,bujinkeyibangzhugejiyishengkuaisuwanchengzhenduanyitigaogongzuoxiaolv,gengzhongyaodeyiyizaiyunengzuidafanweitishengduijicengyisheng、nianqingyishengchugaozhiliangweijingjianchazhenduan、bingzhiyinzhiliao。”

 

huaxiyiyuanyuanzhangliweiminbiaoshi:“huaxi-xishiyixuerengongzhinengyanfazhongxin,jishisichuandaxuehuaxiyiyuanchanxueyanyongxietongchuangxindezhongdakejizhuanhuapingtai,yeshihuaxiyiyuanyikaifangzitaishifangyiyuanziyuandezhongyaobiaozhi。”

 

与华西的合作为AI技术的应用带来了很好的通道。可以想象,华西与希氏异构的“联姻”为其AI技术深深地打上了“华西”的烙印,华西医院本身的体量很大,其下属医联体就更多,技术成熟后的第一应用领域似乎不言而喻,更不用说华西在医疗行业的感召力。

 

希氏异构与华西的合作不仅仅是目前的消化、病理、超声、CT、磁共振等独立的领域,更多的真正体现AI魅力的医学多学科的协同研发的临床应用技术才是他们阶段性的目标。据悉,华西与希氏异构已经开始申报多个省级和国家级的重大项目。

 

两种商业化落地方案已经在实施

 

在商业化方面,希氏异构已经有两方面的准备,一是医疗设备,二是医疗服务。

 

对于医疗设备,公司有两种产品推出:第一种,以技术授权的方式与消化内镜生产商合作,changshangmeimaichuyitairengongzhinengneijingshebei,xishiyigoujiuhuicongzhonghuoli。

 

muqiangongsiyiquedinglediyijiahezuoqiye——shanghaichengyunyiliaoshebeigufenyouxiangongsi,tamennianneijianglianhedazaiaijishudexiaohuaneijing,zheijiyoukenengshiguojishangdiyitairengongzhinengxiaohuaneijing。

 

gaineijingshijiyuzaoyiqudeguojiaxukedeshebeisuozuodejishugengxinchanpin,wuxujingguofuzadexinchanpindebaopiliucheng,yujimingniankeyihuozhunshangshi。zheizhonghezuomoshijishihechuantongxiaohuaneijingyeshihejiaonangneijing。

 

第二种是针对医疗机构已经存在的消化内镜,xishiyigouyanfachuxiaohuaneijingpandingyiqi,zheigeshebeikeyiyuxiaohuaneijingjiehe,bangzhuyishengjinxingpanduan。yuji6geyuenadaocfda 2leiqixierenzheng。

 

对于医疗服务,希氏异构已着手与一流医疗机构的合作,联合推出轻资产的第三方医疗诊断中心的服务。“womenyiaijishujiayiliulinchuangzhuanjiadefangshifuwuyugejiyiliaojigoubaokuotijianzhongxin,nikeyixuanzeshiyongbutongdefuwu,keyishishoufeifeichangdiliandeaifuwu,yekeyishiyouzhimingzhuanjiajichuzhenduanjieguodefuwu。womenzhiweiyiliaojigoutigonggaoshuipingdeyiliaozhichi,rangtamenkuaisukaizhanguoquwunengshunlizhankaideyewu,danwomenbuhuijiechuhuanzhe,zheiyangkenenghuiyougengduodeyiyuanyuanyigenwomenhezuo。”

 

“jicengyiyuandebangeyishengdegongzi,shiwomentigongbuxianliangdeaijishufuwudeshoufeibiaozhun,xiangxin,zheiyangdedaijia,henduoyiyuandouhuiyuanyifuchude。”tandaoyiliaofuwu,songjiezheiyangshuo。

 

congliniandaoyiliaohejishutuandui,congjisuannenglidaoxunlianshuju,conghezuofangdaoshangyehualuodifangan,xishiyigouyongyouzijidutedeyoushi,zheiyeshixishiyigouganyuyuzhongbutongdeziben。

 

关于与资本的对接,宋捷表示,希氏只在天使阶段做过一次融资,目前打算进行新一轮的融资,资金主要用在这几个方面:完善消化AI,包括设备和服务两大产品的推出;年底在病理、影像方面做出突破;建设轻资产的AI+专家模式的第三方诊断中心。

 

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